So, the new options under advanced do the following:
So, you can skip the tutorial (starting you on Lago talking to Les, having just docked with your Remora).
You can skip the “tutorial NPCs” (which means removing the tutorial-esque mini-quests you can find on statiosn at the beginning).
And finally, with sandbox mode, it removes ALL stories/quests, leaving you just with the procedural content.
Or perhaps “begin with full knowledge of all sectors”?
That might be easy and work well.